1. To make lean; to cause to waste away. [Obs. or R.]
2. To subdue the appetites of by poor and scanty diet; to mortify.
3. To soften by steeping in a liquid, with or without heat; to wear away or separate the parts of by steeping; as, to macerate animal or vegetable fiber.
so now do I give a farewell to the world, meaning rather to macerate myself with melancholy, than pine in folly
John Lyly. Euphues: The Anatomy of Wit, (1578)
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SUB. Take away the recipient,
And rectify your menstrue from the phlegma.
Then pour it on the Sol, in the cucurbite,
And let them macerate together.
Ben Jonson. The Alchemist (1610)
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in spite of experience supposed to be finished off with the drama of Laure—in spite too of medicine and biology; for the inspection of macerated muscle or of eyes presented in a dish (like Santa Lucia's), and other incidents of scientific inquiry, are observed to be less incompatible with poetic love than a native dulness or a lively addiction to the lowest prose.